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Bacterial wilt is an important disease of tomato caused by Ralstonia solanacearum, which causes 90% yield losses. The present research was done to evaluate the effect of different chemicals against bacterial wilt of tomato. By using inhibition zone technique, five chemicals (Oxyrich, Forum top, Electus Super, Cabriotop and Kocide) at three different concentrations (250, 300 and 350 ppm) along with control were evaluated against R. solanacearum under lab conditions with Complete Randomized Design (CRD). Among all the treatments, maximum inhibition zone was expressed by Oxyrich (20.687mm). Under field conditions using Randomized Complete Block Design (RCBD), Oxyrich and kocide were evaluated alone and in combination at three different concentrations (2, 2.5 and 3%) along with control. Among these treatments, maximum reduction in disease incidence was expressed by combination of Oxyrich + Kocide (18.38%). Difference among treatments was observed using least significant difference (LSD) at probability level of 0.05%. It is concluded that identification of different chemicals will be helpful in future studies for the management of bacterial wilt disease of tomato.